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Journal of AOAC International - Gravimetric method for the determination of diclofenac in pharmaceutical preparations
January 12th, 2009A gravimetric method for the determination of diclofenac in pharmaceutical preparations was developed. Diclofenac is precipitated from aqueous solution with copper(II) acetate in pH 5.3 (acetic acid/acetate buffer). Sample aliquots had approximately the same quantity of the drug con…
Life Extension - Oral enzyme combination versus diclofenac in the treatment of osteoarthritis of the knee—a double-blind prospective randomized study
January 8th, 2009The aim of this study was to compare the efficacy and safety of an oral enzyme-rutosid combination (ERC) containing rutosid and the enzymes bromelain and trypsin, with that of diclofenac in patients with osteoarthritis (OA) of the knee. A total of 103 patients presenting with painful episodes of OA of the knee were treated for 6 weeks in two study centers in a randomized, double-blind, parallel group trial…
Business Wire - Dyloject™ Significantly Reduces Moderate-to-Severe Pain in Pivotal Phase 3 Orthopedic Surgical Trial
January 5th, 2009 Trial Successful, Javelin Pharmaceuticals on Track to Submit New Drug Application to US FDA in 2009
CAMBRIDGE, Mass. — Javelin Pharmaceuticals (AMEX: JAV) announced today that its US product candidate Dyloject(TM) (diclofenac sodium for injection) met primary efficacy endpoints with rob…
Chemistry and Industry - India moves to protect vultures
January 4th, 2009The Indian government has ordered a crackdown on the illegal use of diclofenac for veterinary purposes, in a last-ditch bid to avert the extinction of vultures threatened by the drug (C&I 2008, 4. 18). Last month, Indian drug controller general Surinder Singh wrote to more…
Journal of Drugs in Dermatology - Diclofenac sodium 3% gel in the treatment of Actinic keratoses Postcryosurgery
December 30th, 2008 Abstract
Background: Actinic keratoses are increasingly common skin lesions that are evaluated and treated by dermatologists on a daily basis. It is estimated that more than 90% of actinic keratoses in the US are treated by destructive therapies, such as cryosurgery. The purpose of this study was to evaluate the efficacy of sequential therapy of cryosurgery foll…
Geographical - India’s government recently announced that it will phase out the veterinary use of Diclofenac
December 24th, 2008India’s government recently announced that it will phase out the veterinary use of Diclofenac, a drug used to treat livestock that has caused a rapid decline in populations of three southern Asian vulture species.
Related Results
DICLOFENAC POTASSIUM.Rofecoxib Is Faster and More Effective Than Diclofenac Sodium in Treating…NPS urges calm on diclofenac use.Diclofenac sodium topical gel for o…
Journal of Avian Medicine and Surgery - J Wildl Dis: Pathology and proposed pathophysiology of diclofenac poisoning in free-living and experimentally exposed oriental white-backed vultures
December 21st, 2008Oriental white-backed vultures (Gyps bengalensis [OWBVs]); died of renal failure when they ingested diclofenac, a nonsteroidal anti-inflammatory drug (NSAID), in tissues of domestic livestock. Acute necrosis of proximal convoluted tubules in these vultures was severe. Glomeruli, distal convoluted tubules, and collecting tubule…
Journal of Drugs in Dermatology - Diclofenac sodium topical gel for osteoarthritis
December 15th, 2008The FDA recently granted approval to Novartis to manufacture and market Voltaren[R] gel. Voltaren gel (diclofenac sodium 1% gel) is approved for the use of pain relief due to osteoarthritis of the knees and hands. Th…
Geographical - A new painkiller could hold the secret to saving three species of vulture in India.(meloxicam to replace diclofenac in treating sick cattle)(Brief article)
December 8th, 2008A new painkiller could hold the secret to saving three species of vulture in India. Populations of Oriental white-backed, long-billed and slender-billed vultures in India have declined by more than 97 per cent since the …
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News: Javelin Presents Successful Pivotal Phase 3 Secondary …
December 4th, 2008Javelin Pharmaceuticals, Inc. (Amex: JAV), a leading developer of
novel products for pain management, today presented new and successful
secondary endpoint data from a previously announced pivotal Phase 3
study of Dyloject(TM). At the 12th World Congress on Pain, held in
Glasgow, Scotland. Dyloject was launched in the United Kingdom in
December of last yea…
